Vaccines (US)

Overview

Bridge Laboratories is an industry leader in vaccine expertise. We have over 15 years of extensive experience performing a wide variety of in vivo toxicology studies that examine the effect of compounds on the immune system. We specialize in the development of vaccines in Biosafety Level-2 (BSL-2) laboratories in the US. Our experienced in-life and post-life staff works to determine safety, immune response and biodistribution over a variety of species, routes of administration and vaccine types.

Vaccine Studies

• Biodistribution and integration

• General toxicology/safety

• Immunogenicity

• In vivo adjuvant selection

Vaccine Types

• DNA plasmid

• Live attenuated

• Peptide

• Prime-boost strategies

• Recombinant protein

• Recombinant vector

• Virus-like particle

Animal Species

• Rabbit

• Mouse

• Rat

• Primate

Routes of Administration

• Dermal (patch)

• Intradermal (Biojector, eletroporation)

• Intramuscular (Biojector)

• Intranasal

• Intravesicular

• Subcutaneous

• Other methods

Vaccine Experience

• Facilities with BSL-2 ratings

• In-life team

• Necropsy team

• Over 130 general vaccine toxicity studies, including: Ebola, HIV, dengue, plague, WNV, SARS, malaria, Boltulin toxin, several cancers, etc.

• Over 40 biodistribution studies

• Biodistribution necropsy (sterilized necropsy techniques)

• Internal clinical pathology analyses

• Internal histopathology evaluation